Substance is donated in a way tht is similar to giving blood. A needle is inserted into the donor's arm in the vein. The plasma is then collected through a process called plasmaphereis and taken through cycles to separate the life saving plasma from the blood.
Hours of operation of most centers is from 7:00 a.m. to 7:00 p.m. You have to be a healthy person to make donations of plasma, and prior to donating people must take a physical exam. This exam is usually done by a registered nurse or doctor on duty.